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Article

Interactive effects of MC1R and OCA2 on melanoma risk phenotypes.

Human molecular genetics - 15 Feb 2004

Duffy David L, Box Neil F, Chen Wei, Palmer James S, Montgomery Grant W, James Michael R, Hayward Nicholas K, Martin Nicholas G, Sturm Richard A

Abstract excerpt

The relationships between MC1R gene variants and red hair, skin reflectance, degree of freckling and nevus count were investigated in 2331 adolescent twins, their sibs and parents in 645 twin families. Penetrance of each MC1R variant allele was consistent with an allelic model where effects were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14709592
DOI: 10.1093/hmg/ddh043

Genes

OCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14709592-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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