Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2.

doi:10.1126/science.1470921

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Article

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2.

Science (New York, N.Y.) - 18 Dec 1992

Vaux D L, Weissman I L, Kim S K

Abstract excerpt

Programmed cell death is a physiological process that eliminates unwanted cells. The bcl-2 gene regulates programmed cell death in mammalian cells, but the way it functions is not known. Expression of the human bcl-2 gene in the nematode Caenorhabditis elegans reduced the number of programmed cel...

Topics

Animals
Animals, Genetically Modified
Caenorhabditis elegans
Cell Death
Embryo, Nonmammalian
GTP-Binding Proteins
Gene Expression
Genotype
Humans
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcl-2

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