Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2.

Science (New York, N.Y.) - 18 Dec 1992

Vaux D L, Weissman I L, Kim S K

Abstract excerpt

Programmed cell death is a physiological process that eliminates unwanted cells. The bcl-2 gene regulates programmed cell death in mammalian cells, but the way it functions is not known. Expression of the human bcl-2 gene in the nematode Caenorhabditis elegans reduced the number of programmed cell deaths, suggesting that the mechanism of programmed cell death controlled by bcl-2 in humans is the same as that in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to Animals, Genetically Modified
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Death

Share to Embryo, Nonmammalian

Share to Gene Expression

Share to GTP-Binding Proteins

Share to Proto-Oncogene Proteins

Source

Identifiers

PMID: 1470921
DOI: 10.1126/science.1470921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2.PMID 1470921Read ↗

Role of Bcl-2 family members in invertebratesSemantic proximity Read ↗

Regulation of apoptosis by Bcl‐2 family proteinsSemantic proximity Read ↗

BCL-2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy.Semantic proximity Read ↗

BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapySemantic proximity Read ↗

Inhibitors of the anti-apoptotic Bcl-2 proteins: a patent reviewSemantic proximity Read ↗

BCL-2 family members in the development and degenerative pathologies of the nervous systemSemantic proximity Read ↗

Apoptosis in<i>Drosophila</i>: neither fish nor fowl (nor man, nor worm)Semantic proximity Read ↗

Iridovirus Bcl-2 protein inhibits apoptosis in the early stage of viral infectionSemantic proximity Read ↗

Bcl-2 Inhibition of Autophagy: A New Route to Cancer?Semantic proximity Read ↗

Apoptosis and predisposition to oral cancer.Semantic proximity Read ↗

Noncanonical cell death programs in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

The Human Bcl-2 Family Member Bcl-rambo Localizes to Mitochondria and Induces Apoptosis and Morphological Aberrations in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.