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Article

Differentiation and Migration of Bone Marrow Mesenchymal Stem Cells Transplanted through the Spleen in Rats with Portal Hypertension

10 Dec 2013

Abstract excerpt

AIMS: The goals of this paper were to evaluate the differentiation of bone marrow mesenchymal stem cells (BMSCs) into hepatocyte-like cells in vitro, and to determine whether stem cells can migrate and plant into the liver with portal hypertension accompanied by the end-stage of liver disease. METHODS: BMSCs were isolated from rats and amplified with hepatocyte growth factor (HGF) and fibroblast growth factor-4...

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PMID: 24340101
DOI: 10.1371/journal.pone.0083523

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