Article
Molecular and Cellular Functions Distinguish Superior Therapeutic Efficiency of Bone Marrow CD45 Cells Over Mesenchymal Stem Cells in Liver Cirrhosis.
Stem cells (Dayton, Ohio) - 1 Jan 2016
Baligar Prakash, Mukherjee Snehasish, Kochat Veena, Rastogi Archana, Mukhopadhyay Asok
Abstract excerpt
Liver fibrosis is strongly associated with chronic inflammation. As an alternative to conventional treatments for fibrosis, mesenchymal stem cells (MSCs) therapy is found to be attractive due to its immunomodulatory functions. However, low survival rate and profibrogenic properties of MSCs remain the major concerns, leading to skepticism in many investigators. Here, we have asked the question whether bone marrow...
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