Article
Hepatic lineages isolated from developing rat liver show different ways of maturation.
Biochemical and biophysical research communications - 23 May 2003
Fiegel Henning C, Kluth Jantjeline, Lioznov Michael V, Holzhüter Stephanie, Fehse Boris, Zander Axel R, Kluth Dietrich
Abstract excerpt
Immunocytochemical analysis revealed that different hepatic cell types exist during liver development: (i). cells co-expressing the stem-cell marker Thy1 and the hepatic lineage marker CK-18 and (ii). cells only expressing CK-18 (hepatoblasts). In this study we separated the different hepatic cells and analyzed gene-expression and phenotype. Fetal rat livers were digested by collagenase solution. OX43- and...
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