Article
The human model: a genetic dissection of immunity to infection in natural conditions.
Nature reviews. Immunology - 1 Jan 2004
Casanova Jean-Laurent, Abel Laurent
Abstract excerpt
Tremendous progress has been achieved in developmental, cellular and molecular immunology in the past 20 years, largely due to studies using the mouse as a model system and the arrival of molecular genetics. Immunology is now faced with a difficult challenge. What are the functions of the individual cells and molecules in achieving immunity to infection? Renewed interest in animal models of disease has provided...
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