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Article

Dynamic changes in expression of myosin phosphatase in a model of portal hypertension.

American journal of physiology. Heart and circulatory physiology - 1 May 2004

Payne Michael C, Zhang Hai-Ying, Shirasawa Yuichi, Koga Yasuhiko, Ikebe Mitsuo, Benoit Joseph N, Fisher Steven A

Abstract excerpt

Myosin phosphatase is a target for signaling pathways that modulate calcium sensitivity of force production in smooth muscle. Myosin phosphatase targeting subunit 1 (MYPT1) isoforms are generated by cassette-type alternative splicing of exons in the central and 3' portion of the transcript. Exclusion of the 3' alternative exon, coding for the leucine zipper (LZ)-positive MYPT1 isoform, is associated with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14704233
DOI: 10.1152/ajpheart.00696.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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