Article
GATA transcription factors and fat cell formation
1 Jan 2003
Abstract excerpt
GATA transcription factors play important roles in a variety of developmental processes. Recently, we discovered that GATA factors also play a key role in adipogenesis. Two isoforms, GATA-2 and GATA-3, are specifically expressed in murine preadipocytes but not mature adipocytes. Continuous expression of GATA factors in preadipocyte cell lines inhibits terminal differentiation into mature adipocytes. In contrast,...
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