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Article

DRD4 rare variants in Attention-Deficit/Hyperactivity Disorder (ADHD): further evidence from a birth cohort study.

PloS one - 1 Jan 2013

Tovo-Rodrigues Luciana, Rohde Luis A, Menezes Ana M B, Polanczyk Guilherme V, Kieling Christian, Genro Julia P, Anselmi Luciana, Hutz Mara H

Abstract excerpt

The dopamine receptor D4 (DRD4) is one of the most studied candidate genes for Attention-Deficit/Hyperactivity Disorder (ADHD). An excess of rare variants and non-synonymous mutations in the VNTR region of 7R allele in ADHD subjects was observed in previous studies with clinical samples. We hypothesize that genetic heterogeneity in the VNTR is an important factor in the pathophysiology of ADHD. The subjects...

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PMID: 24391992
DOI: 10.1371/journal.pone.0085164
PMCID: PMC3877354

Genes

DRD4

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Source receipt: pubmed, retrieved 7 Sept 2026.

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