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Article

The rad50 signature motif: essential to ATP binding and biological function.

Journal of molecular biology - 23 Jan 2004

Moncalian Gabriel, Lengsfeld Bettina, Bhaskara Venugopal, Hopfner Karl-Peter, Karcher Annette, Alden Erinn, Tainer John A, Paull Tanya T

Abstract excerpt

The repair of double-strand breaks in DNA is an essential process in all organisms, and requires the coordinated activities of evolutionarily conserved protein assemblies. One of the most critical of these is the Mre11/Rad50 (M/R) complex, which is present in all three biological kingdoms, but is not well-understood at the biochemical level. Previous structural analysis of a Rad50 homolog from archaebacteria...

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Share to Acid Anhydride Hydrolases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14698290
DOI: 10.1016/j.jmb.2003.11.026

Genes

CFTR
RAD50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The rad50 signature motif: essential to ATP binding and biological function.PMID 14698290Read ↗

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