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Article

A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM2.

Biochemical and biophysical research communications - 16 Jan 2004

Yamaki Akiko, Kudoh Jun, Shimizu Nobuyoshi, Shimizu Yoshiko

Abstract excerpt

Human Single-minded 1 (SIM1) and SIM2 genes were found as homologs of Drosophila sim gene which plays a key role in the midline cell lineage of the central nervous system. SIM proteins belong to a family of transcription factors, called bHLH/PAS. Here we examined the intracellular localization of SIM proteins using the expression constructs of whole SIM2 or SIM1 protein fused with enhanced green fluorescent...

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Source

Identifiers

PMID: 14697214
DOI: 10.1016/j.bbrc.2003.11.168

Genes

SIM2
SIM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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