Article
Transcriptional activation domains of the single-minded bHLH protein are required for CNS midline cell development.
Mechanisms of development - 1 Mar 1994
Franks R G, Crews S T
Abstract excerpt
The single-minded gene functions as a master developmental regulator within the midline cell lineage of the embryonic central nervous system of Drosophila melanogaster. Genetic experiments suggest that Single-minded can function as a transcriptional activator. Regions of the Single-minded protein...
Topics
- Animals
- Cells, Cultured
- Central Nervous System
- Cloning, Molecular
- Drosophila melanogaster
- Gene Expression Regulation
- Helix-Loop-Helix Motifs
- Nuclear Proteins
- Phenotype
- Protein Binding
- Sp1 Transcription Factor
- Trans-Activators
- Transformation, Genetic