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Article

Transcriptional activation domains of the single-minded bHLH protein are required for CNS midline cell development.

Mechanisms of development - 1 Mar 1994

Franks R G, Crews S T

Abstract excerpt

The single-minded gene functions as a master developmental regulator within the midline cell lineage of the embryonic central nervous system of Drosophila melanogaster. Genetic experiments suggest that Single-minded can function as a transcriptional activator. Regions of the Single-minded protein were fused to the DNA binding domain of the mammalian transcription factor Sp1 and shown to activate transcription...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8011558
DOI: 10.1016/0925-4773(94)90013-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transcriptional activation domains of the single-minded bHLH protein are required for CNS midline cell development.PMID 8011558Read ↗

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