Article
Novel behavioral and developmental defects associated with Drosophila single-minded.
Developmental biology - 15 Sept 2002
Pielage Jan, Steffes Georg, Lau Dan C, Parente Beth A, Crews Stephen T, Strauss Roland, Klämbt Christian
Abstract excerpt
In Drosophila, the development of the midline cells of the embryonic ventral nerve cord depends on the function of the bHLH-PAS transcription factor Single-minded (Sim). The expression domain of sim, however, is also found anterior and posterior to the developing ventral cord throughout the germ band. Indeed, mutations in sim were identified based on their characteristic cuticle phenotype. Eight abdominal...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Basic Helix-Loop-Helix Transcription Factors
- Behavior, Animal
- DNA Primers
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Embryo, Nonmammalian
- Female
- Gene Expression Regulation, Developmental
- Helix-Loop-Helix Motifs