Article
NF-κB p65 Antagonizes IL-4 Induction by c- maf in Minimal Change Nephrotic Syndrome
1 Jan 2004
Abstract excerpt
Mechanisms underlying the pathophysiology of minimal change nephrotic syndrome (MCNS), the most frequent of glomerular diseases in children, remain elusive, although recent arguments suggest that T cell dysfunction may be involved in the pathogenesis of this disease. Recently, we reported that activated T cells of these patients display a down-regulation of IL-12R beta2 chain, suggesting an early commitment...
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