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Article

Role of hyphal formation in interactions of Candida albicans with endothelial cells.

Infection and immunity - 1 Jun 2000

Phan Q T, Belanger P H, Filler S G

Abstract excerpt

The ability to change from yeast to hyphal morphology is a major virulence determinant of Candida albicans. Mutants with defined defects in filamentation regulatory pathways have reduced virulence in mice. However, is it poorly understood why hyphal formation is critical for C. albicans to cause hematogenously disseminated infections. We used recently constructed mutants to examine the role of hyphal formation in...

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Identifiers

PMID: 10816502
DOI: 10.1128/IAI.68.6.3485-3490.2000
PMCID: PMC97632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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