Article
Candida albicans Ecm33p is important for normal cell wall architecture and interactions with host cells.
Eukaryotic cell - 1 Jan 2006
Martinez-Lopez Raquel, Park Hyunsook, Myers Carter L, Gil Concha, Filler Scott G
Abstract excerpt
Candida albicans ECM33 encodes a glycosylphosphatidylinositol-linked cell wall protein that is important for cell wall integrity. It is also critical for normal virulence in the mouse model of hematogenously disseminated candidiasis. To identify potential mechanisms through which Ecm33p contributes to virulence, we investigated the interactions of C. albicans ecm33Delta mutants with endothelial cells and the FaDu...
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