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Article

Expression, purification, and characterization of His20 mutants of rat mevalonate kinase.

Protein expression and purification - 1 Nov 2003

Chu Xiusheng, Li Ding

Abstract excerpt

Mevalonate kinase plays a key role in regulating the biosynthesis of cholesterol in animal cells. Human mevalonate kinase His20Pro has been reported as one of the three common mutations in the mevalonate kinase gene in mevalonic aciduria and hyperimmunoglobulinemia D/periodic fever syndrome patie...

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PMID: 14680942
DOI: 10.1016/S1046-5928(03)00221-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14680942-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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