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Article

The arginine-16 beta2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol.

British journal of clinical pharmacology - 1 Jan 2004

Lee Daniel K C, Currie Graeme P, Hall Ian P, Lima John J, Lipworth Brian J

Abstract excerpt

AIMS: The relationship between beta2-adrenoceptor polymorphisms and bronchoprotective response with long-acting beta2-adrenoceptor agonists is unknown. METHODS: We retrospectively analysed data from six placebo-controlled randomized studies in corticosteroid treated asthmatics where formoterol or salmeterol were administered over a 1-2-week period, with prior 1-2 week washout, assessing the primary end point of...

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Identifiers

PMID: 14678342
DOI: 10.1046/j.1365-2125.2003.01955.x
PMCID: PMC1884417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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