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Article

The CAG repeats in exon 1 of the androgen receptor gene are significantly longer in endometrial cancer patients.

Biochemical and biophysical research communications - 13 Jun 2003

Sasaki Masahiro, Sakuragi Noriaki, Dahiya Rajvir

Abstract excerpt

Human androgen receptor (AR) gene contains polymorphic CAG repeats in the N-terminal domain that influence transcription efficiency. The CAG repeats encode a poly-glutamine tract, which has a length that is inversely and linearly related to AR activity. It has been observed that longer CAG repeats impose a lower transactivation activity on AR and have a decreased binding affinity for androgens. Androgens have an...

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Identifiers

PMID: 12767946
DOI: 10.1016/s0006-291x(03)00883-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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