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Article

Role for BRG1 in cell cycle control and tumor suppression.

Molecular and cellular biology - 1 Jan 2004

Hendricks Kristin B, Shanahan Frances, Lees Emma

Abstract excerpt

Human BRG1, a subunit of the Swi/Snf chromatin remodeling apparatus, has been implicated in regulation of cellular proliferation and is a candidate tumor suppressor. Reintroduction of BRG1 into a breast tumor cell line, ALAB, carrying a defined mutation in the BRG1 gene, induced growth arrest. Gene expression data revealed that the arrest may in part be accounted for by down-regulation of select E2F target genes...

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Source

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Identifiers

PMID: 14673169
DOI: 10.1128/MCB.24.1.362-376.2004
PMCID: PMC303366

Genes

CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Role for BRG1 in cell cycle control and tumor suppression.PMID 14673169Read ↗

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