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Mullerian Inhibiting Substance inhibits cervical cancer cell growth via a pathway involving p130 and p107

11 Dec 2003

Abstract excerpt

In addition to causing regression of the Mullerian duct in the male embryo, Mullerian Inhibiting Substance (MIS) inhibits the growth of epithelial ovarian cancer cells, which are known to be of Mullerian origin. Because the uterine cervix is derived from the same Mullerian duct precursor as the epithelium of the ovary, we tested the hypothesis that cervical cancer cells might also respond to MIS. A number of...

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Share to Ovarian cancer diagnosis and treatment
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PMID: 14671316
DOI: 10.1073/pnas.2636900100

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