Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Müllerian Inhibiting Substance Inhibits Breast Cancer Cell Growth through an NFκB-mediated Pathway

1 Sept 2000

Abstract excerpt

Müllerian inhibiting substance (MIS), a member of the transforming growth factor-beta superfamily, induces regression of the Müllerian duct in male embryos. In this report, we demonstrate MIS type II receptor expression in normal breast tissue and in human breast cancer cell lines, breast fibroadenoma, and ductal adenocarcinomas. MIS inhibited the growth of both estrogen receptor (ER)-positive T47D and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics, phytochemicals, and oxidative stress
Share to Ginseng Biological Effects and Applications
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10874041
DOI: 10.1074/jbc.m004554200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Müllerian Inhibiting Substance Inhibits Breast Cancer Cell Growth through an NFκB-mediated PathwayPMID 10874041Read ↗

Müllerian Inhibiting Substance Regulates NFκB Signaling and Growth of Mammary Epithelial Cells in VivoSemantic proximity Read ↗

Müllerian Inhibiting Substance Inhibits Ovarian Cell Growth through an Rb-independent MechanismSemantic proximity Read ↗

Endometrial cancer is a receptor-mediated target for Mullerian Inhibiting SubstanceSemantic proximity Read ↗

Mullerian Inhibiting Substance inhibits cervical cancer cell growth via a pathway involving p130 and p107Semantic proximity Read ↗

New insights into mullerian inhibiting substance and its mechanism of actionSemantic proximity Read ↗

Mullerian Inhibiting Substance: A Gonadal Hormone with Multiple Functions*Semantic proximity Read ↗

Mullerian inhibiting substance: an update.Semantic proximity Read ↗

The müllerian inhibitor and mammalian sexual development.Semantic proximity Read ↗

Genetic analysis of the Müllerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation.Semantic proximity Read ↗

Synergistic Cooperation between the β-Catenin Signaling Pathway and Steroidogenic Factor 1 in the Activation of the Mullerian Inhibiting Substance Type II ReceptorSemantic proximity Read ↗

A single base pair mutation encoding a premature stop codon in the MIS type II receptor is responsible for canine persistent Müllerian duct syndrome.Semantic proximity Read ↗

Mullerian Inhibiting Substance Signaling Uses a Bone Morphogenetic Protein (BMP)-Like Pathway Mediated by ALK2 and Induces Smad6 ExpressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.