Article
Tellimagrandin I enhances gap junctional communication and attenuates the tumor phenotype of human cervical carcinoma HeLa cells in vitro.
Cancer letters - 8 Oct 2006
Yi Zong-Chun, Liu Yan-Ze, Li Hai-Xia, Yin Yan, Zhuang Feng-Yuan, Fan Yu-Bo, Wang Zhao
Abstract excerpt
Tellimagrandin I and chebulinic acid, two hydrolysable tannins, have been shown to exert anti-tumor properties. Dysfunctional gap junctional communication (GJIC) has been recognized as being involved in carcinogenesis. The human cervical carcinoma HeLa cells have been reported to be deficient in functional GJIC. In present study, we investigated whether tellimagrandin I and chebulinic acid might restore...
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