Article
Exon 6 and 2 peroxisome proliferator-activated receptor-gamma polymorphisms in polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism - 1 Dec 2003
Orio Francesco, Matarese Giuseppe, Di Biase Sebastiano, Palomba Stefano, Labella Donato, Sanna Veronica, Savastano Silvia, Zullo Fulvio, Colao Annamaria, Lombardi Gaetano
Abstract excerpt
Obesity affects about 44% of women with polycystic ovary syndrome (PCOS). Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) is one of the genes involved in the differentiation of adipose tissue. In an attempt to shed light on the high percentage of obesity in PCOS, we examined polymorphisms at exons 6 and 2 of the PPAR-gamma gene in 100 PCOS patients and in 100 healthy controls matched for age and...
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