Article
Cytokine secretion by cystic fibrosis airway epithelial cells.
American journal of respiratory and critical care medicine - 1 Mar 2004
Becker Marie N, Sauer Mariam S, Muhlebach Marianne S, Hirsh Andrew J, Wu Qi, Verghese Margrith W, Randell Scott H
Abstract excerpt
It is controversial whether mutations in cystic fibrosis transmembrane conductance regulator intrinsically dysregulate inflammation. We characterized passage 2 human tracheobronchial epithelial cell cultures morphologically and physiologically and determined whether cytokine production or nuclear factor-kappaB activation was systematically altered in cystic fibrosis (CF) cells. Non-CF and CF cells originating...
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