Article
Pro-inflammatory effects of Burkholderia cepacia on cystic fibrosis respiratory epithelium.
FEMS immunology and medical microbiology - 15 Oct 2003
Fink Joshua, Steer James H, Joyce David A, McWilliam Andrew S, Stewart Geoffrey A
Abstract excerpt
Burkholderia cepacia causes pulmonary infection with high mortality in cystic fibrosis (CF) patients which is likely to involve interaction with respiratory epithelium. In this study the pro-inflammatory properties of B. cepacia were examined using a range of respiratory epithelial cell lines. B. cepacia and cell-free culture supernatants were used to stimulate cell lines with (SigmaCFTE29o- and IB3) and without...
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