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Article

Structural diversity and functional implications of the eukaryotic TDP gene family.

Genomics - 1 Jan 2004

Wang Hurng-Yi, Wang I-Fan, Bose Jayaramakrishnan, Shen C-K James

Abstract excerpt

TDP-43 is an RNA-binding protein that functions in mammalian cells in transcriptional repression and exon skipping. The gene encoding TDP-43 (HGMW-approved gene symbol TARDBP) is conserved in human, mouse, Drosophila melanogaster, and Caenorhabditis elegans. Sequence comparison of the coding regions of the TDP genes among the four taxa reveals an extraordinarily low rate of sequence divergence, suggesting that...

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Identifiers

PMID: 14667816
DOI: 10.1016/s0888-7543(03)00214-3

Genes

TARDBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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