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Article

A gene containment strategy based on a restriction-modification system.

Environmental microbiology - 1 Oct 2000

Torres B, Jaenecke S, Timmis K N, García J L, Díaz E

Abstract excerpt

Engineering barriers to the spread of specific genes are of great interest both to increase the predictability of recombinant microorganisms used for environmental applications and to study the role of gene transfer in the adaptation of microbial communities to changing environments. We report here a new gene containment circuit based on a toxin-antidote pair that targets the cell DNA, i.e. the type II EcoRI...

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Share to Deoxyribonuclease EcoRI
Share to DNA, Bacterial
Share to DNA Modification Methylases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Environmental Microbiology

Share to Gene Transfer, Horizontal

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Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 11233163
DOI: 10.1046/j.1462-2920.2000.00138.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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