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Article

Denaturing high-performance liquid chromatography for detecting and typing genital human papillomavirus.

Journal of clinical microbiology - 1 Dec 2003

Li Jianduan, Gerhard Daniela S, Zhang Zhengyan, Huettner Phyllis C, Wright Jason, Nguyen Loan, Lu Danielle, Rader Janet S

Abstract excerpt

Human papillomaviruses (HPVs) are important in the development of human cancers, including cervical and oral tumors. However, most existing methods for HPV typing cannot routinely distinguish among the more than 100 distinct types of HPV or the natural HPV intratypic variants that have also been documented. To address this problem, we developed a novel method, general primer-denaturing high-performance liquid...

Topics

Base Sequence
Chromatography, High Pressure Liquid
Codon
DNA Primers
Female
Genes, Viral
Genotype
Humans
Papillomaviridae
Papillomavirus Infections
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sensitivity and Specificity

Tumor Virus Infections

Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 14662941
DOI: 10.1128/JCM.41.12.5563-5571.2003
PMCID: PMC309016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-14662941-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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