Article
Development of a simplified and cost-effective sample preparation method for genotyping of human papillomavirus by next-generation sequencing.
Archives of virology - 20 Jun 2023
Jitvaropas Rungrat, Thongpoom Ukrit, Sawaswong Vorthon, Khongnomnan Kritsada, Poomipak Witthaya, Praianantathavorn Kesmanee, Nilyanimit Pornjarim, Poovorawan Yong, Payungporn Sunchai
Abstract excerpt
High-risk human papillomavirus (HPV) infection is the most common cause of cervical cancer, but low-risk HPV strains can sometimes also be involved. Although HPV genotyping techniques used in clinical diagnosis cannot detect low-risk HPV, next-generation sequencing (NGS) can detect both types. However, DNA library preparation is complicated and expensive. The aim of this study was to develop a simplified,...
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