Article
The TPTE gene family: cellular expression, subcellular localization and alternative splicing.
Gene - 24 Dec 2003
Tapparel Caroline, Reymond Alexandre, Girardet Christophe, Guillou Louis, Lyle Robert, Lamon Christine, Hutter Pierre, Antonarakis Stylianos E
Abstract excerpt
The human TPTE (Transmembrane Phosphatase with TEnsin homology) gene family encodes a PTEN-related tyrosine phosphatase with four potential transmembrane domains. Chromosomal mapping revealed multiple copies of the TPTE gene on chromosomes 13, 15, 21, 22 and Y. Human chromosomes 13 and 21 copies encode two functional proteins, TPIP (TPTE and PTEN homologous Inositol lipid Phosphatase) and TPTE, respectively,...
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