Article
Otosclerosis: exclusion of linkage to the OTSC1 and OTSC2 loci in four Italian families.
International journal of audiology - 1 Dec 2003
Di Leva Francesca, D'Adamo Adamo Pio, Strollo Luiaino, Auletta Gennaro, Caravelli Antonella, Carella Massimo, Mari Francesca, Livi Walter, Renieri Alessandra, Gasparini Paolo, D'Urso Michele, Marciano Elio, Franzé Annamaria
Abstract excerpt
Otosclerosis is the single most common cause of hearing impairment among adult caucasians. Little is known about its aetiology and its molecular aspects. Until now, genetic linkage in otosclerosis has been demonstrated in an Indian family and a Belgian family, showing the presence of two otosclerosis loci, OTSC1 and OTSC2, respectively. Linkage analysis has never been applied to Italian otosclerotic families. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.