Article
High contribution contrast between the genes of eosinophil peroxidase and IL-4 receptor alpha-chain in Japanese cedar pollinosis.
The Journal of allergy and clinical immunology - 1 Dec 2003
Nakamura Hiroyuki, Miyagawa Kiyoshi, Ogino Keiki, Endo Tomohiko, Imai Toru, Ozasa Kotaro, Motohashi Yutaka, Matsuzaki Ichiyo, Sasahara Shinichiro, Hatta Kotaro, Eboshida Akira
Abstract excerpt
BACKGROUND: Japanese cedar pollinosis is the most common form of hayfever in Japan in spring and has remarkably increased since 1960. OBJECTIVE: We sought to clarify the candidate genes for cedar pollinosis using a case-control study. METHODS: After diagnosing 351 subjects on the basis of an intradermal test, nasal provocation test, and questionnaire regarding nasal and conjunctival symptoms, we determined the...
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