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Article

Polymorphism of the immune‐braking gene CTLA‐4 (+49) involved in gender discrepancy of serum total IgE levels and allergic diseases

1 Jan 2004

Abstract excerpt

BACKGROUND: A variety of genes are related to allergic disorders in different ethnic populations. The genetic basis for the gender discrepancy of allergic diseases remains to be determined. OBJECTIVE: This study was conducted to investigate whether IL-4 promoter (-590 C/T) and cytotoxic T lymphocyte antigen 4 (CTLA-4) (+49 A/G) polymorphisms were correlated with a gender discrepancy of total IgE levels and...

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PMID: 14720259
DOI: 10.1111/j.1365-2222.2004.01776.x

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