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Article

Redox regulation of germline and vulval development in Caenorhabditis elegans.

Science (New York, N.Y.) - 5 Dec 2003

Shibata Yukimasa, Branicky Robyn, Landaverde Irene Oviedo, Hekimi Siegfried

Abstract excerpt

In vitro studies have indicated that reactive oxygen species (ROS) and the oxidation of signaling molecules are important mediators of signal transduction. We have identified two pathways by which the altered redox chemistry of the clk-1 mutants of Caenorhabditis elegans acts in vivo on germline development. One pathway depends on the oxidation of an analog of vertebrate low density lipoprotein (LDL) and acts on...

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PMID: 14657502
DOI: 10.1126/science.1087167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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