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Article

The radiation-sensitive mutant rad-8 of Caenorhabditis elegans is hypersensitive to the effects of oxygen on aging and development.

Mechanisms of ageing and development - 1 May 1993

Ishi N, Suzuki N, Hartman P S, Suzuki K

Abstract excerpt

A mutant of rad-8, originally isolated on the basis of its hypersensitivity to ultraviolet radiation, is also hypersensitive to oxygen and methyl viologen, a superoxide-anion generator. Oxygen also retarded development and reduced fecundity in a concentration-dependent fashion in rad-8 but not in wild type. In addition, the mean life span of rad-8 (but not wild type) was progressively shortened when animals...

Read the complete abstract on PubMed

Topics

Aging
Animals
Caenorhabditis elegans
Fertility
Longevity
Mutation
Oxygen

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Paraquat

Radiation Tolerance

Survival Rate

Source

Identifiers

PMID: 8350650
DOI: 10.1016/0047-6374(93)90135-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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