Article
INS VNTR is a QTL for the insulin response to oral glucose in obese children.
Physiological genomics - 13 Feb 2004
Dos Santos Christine, Fallin Daniele, Le Stunff Catherine, LeFur Sophie, Bougnères Pierre
Abstract excerpt
We performed a genotype-phenotype association study to examine whether the insulin VNTR (INS VNTR) polymorphism located in the insulin gene promoter was associated with changes in insulin response to oral glucose. Two classes of INS VNTR alleles are observed in Caucasians, the "short" class I and the "long" class III. Plasma insulin and glucose concentrations and indices of insulin secretion (IGI) and sensitivity...
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