Article
Axonal transport of British and Danish amyloid peptides via secretory vesicles.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2004
Choi Seung-Il, Vidal Ruben, Frangione Blas, Levy Efrat
Abstract excerpt
The ABri and ADan amyloid peptides deposited in familial British and Danish neurodegenerative disorders are generated by processing mutant forms of the precursor protein BRI2. Although the pathogenic process that leads to deposition of amyloid in the brains of patients has been studied extensively, the cellular processes and normal function of the precursor protein did not receive much attention. We observed in a...
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