Article
Molecular correlates of genes exhibiting RNAi phenotypes in Caenorhabditis elegans.
Genome research - 1 Dec 2003
Cutter Asher D, Payseur Bret A, Salcedo Tovah, Estes Anne M, Good Jeffrey M, Wood Elizabeth, Hartl Thomas, Maughan Heather, Strempel Jannine, Wang Baomin, Bryan Anthony C, Dellos Melissa
Abstract excerpt
Understanding genome-wide links between genotype and phenotype has generally been difficult due to both the complexity of phenotypes, and until recently, inaccessibility to large numbers of genes that might underlie a trait. To address this issue, we establish the association between particular RNAi phenotypes in Caenorhabditis elegans and sequence characteristics of the corresponding proteins and DNA. We find...
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