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Article

Delta-promoted filopodia mediate long-range lateral inhibition in Drosophila.

Nature - 4 Dec 2003

De Joussineau Cyrille, Soulé Jonathan, Martin Marianne, Anguille Christelle, Montcourrier Philippe, Alexandre Daniel

Abstract excerpt

Drosophila thoracic mechanosensory bristles originate from cells that are singled out from 'proneural' groups of competent epithelial cells. Neural competence is restricted to individual sensory organ precursors (SOPs) by Delta/Notch-mediated 'lateral inhibition', whereas other cells in the proneural field adopt an epidermal fate. The precursors of the large macrochaetes differentiate separately from individual...

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PMID: 14654840
DOI: 10.1038/nature02157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Delta-promoted filopodia mediate long-range lateral inhibition in Drosophila.PMID 14654840Read ↗

Delta, notch, and shaggy: elements of a lateral signaling pathway in Drosophila.Semantic proximity Read ↗

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Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless.Semantic proximity Read ↗

Exploring the roles of diaphanous and enabled activity in shaping the balance between filopodia and lamellipodia.Semantic proximity Read ↗

Delta function is required for bristle organ determination and morphogenesis in Drosophila.Semantic proximity Read ↗

scabrous modifies epithelial cell adhesion and extends the range of lateral signalling during development of the spaced bristle pattern in Drosophila.Semantic proximity Read ↗

Proneural clusters: equivalence groups in the epithelium of Drosophila.Semantic proximity Read ↗

Optogenetic inhibition of Delta reveals digital Notch signalling output during tissue differentiation.Semantic proximity Read ↗

Notch controls cell adhesion in the Drosophila eye.Semantic proximity Read ↗

Long-range coordination of planar polarity in Drosophila.Semantic proximity Read ↗

The pleiotropic function of Delta during postembryonic development of Drosophila melanogaster.Semantic proximity Read ↗

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