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Article

Conservation of IGF2-H19 and IGF2R imprinting in sheep: effects of somatic cell nuclear transfer.

Mechanisms of development - 1 Dec 2003

Young Lorraine E, Schnieke Angelika E, McCreath Kenneth J, Wieckowski Sébastien, Konfortova Galia, Fernandes Kenneth, Ptak Grazyna, Kind Alex J, Wilmut Ian, Loi Pasqualino, Feil Robert

Abstract excerpt

In different mammalian species, in vitro culture and manipulation can lead to aberrant fetal and peri-natal development. It has been postulated that these diverse abnormalities are caused by epigenetic alterations and that these could affect genes that are regulated by genomic imprinting. To explore this hypothesis relative to somatic cell nuclear transfer in sheep, we investigated whether the ovine H19-IGF2 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14654216
DOI: 10.1016/j.mod.2003.09.006

Genes

IGF2
CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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