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Article

Monoallelic expression of nine imprinted genes in the sheep embryo occurs after the blastocyst stage.

Reproduction (Cambridge, England) - 1 Jan 2008

Thurston Alexandra, Taylor Jane, Gardner John, Sinclair Kevin D, Young Lorraine E

Abstract excerpt

The preimplantation embryos of a range of mammals can be susceptible to disruptions in genomic imprinting mechanisms, resulting in loss of imprinting. Such disruptions can have developmental consequences involving foetal and placental growth such as Beckwith-Wiedemann syndrome in humans and large offspring syndrome in sheep. Our objective was to investigate the dynamics of establishing monoallelic expression of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18159081
DOI: 10.1530/REP-07-0211

Genes

GRB10
CTCF
GNAS
IGF2
PEG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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