Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allele 4G of gene PAI-1 associated with prothrombin mutation G20210A increases the risk for venous thrombosis.

Thrombosis and haemostasis - 1 Dec 2003

Barcellona Doris, Fenu Lara, Cauli Cristiana, Pisu Giulia, Marongiu Francesco

Abstract excerpt

Several studies have tried to clarify the role of polymorphism 4G/5G of the PAI-1 gene in venous thromboembolism without reaching any final conclusion. It has been demonstrated that this polymorphism may induce an increased risk for venous thromboembolism (VTE) in patients with thrombophilic defects. We studied the association of prothrombin mutation G20210A with 4G/5G polymorphism in 402 VTE patients and 466...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Odds Ratio

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Plasminogen Activator Inhibitor 1

Share to Point Mutation

Share to Prothrombin

Share to Thromboembolism

Share to Venous Thrombosis

Source

Identifiers

PMID: 14652637
DOI: 10.1160/TH02-12-0305

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allele 4G of gene PAI-1 associated with prothrombin mutation G20210A increases the risk for venous thrombosis.PMID 14652637Read ↗

Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis. A meta-analysis.Semantic proximity Read ↗

Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosisSemantic proximity Read ↗

The PAI-1 gene 4G/5G polymorphism and deep vein thrombosis in patients with inherited thrombophilia.Semantic proximity Read ↗

Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and risk of venous thromboembolism: a meta-analysis.Semantic proximity Read ↗

PAI-1 promoter 4G/5G genotype as an additional risk factor for venous thrombosis in subjects with genetic thrombophilic defects.Semantic proximity Read ↗

Plasminogen activator inhibitor-1 (PAI-1) 4G/5G promoter polymorphisms and risk of venous thromboembolism - a meta-analysis and systematic review.Semantic proximity Read ↗

Factor V Leiden mutation and PAI-1 gene 4G/5G genotype in thrombotic patients with Behcet's disease.Semantic proximity Read ↗

Investigation of Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G promoter polymorphism in Indian venous thrombosis patients: A case-control study.Semantic proximity Read ↗

4G/5G polymorphism of PAI-1 gene promoter and fibrinolytic capacity in patients with deep vein thrombosis.Semantic proximity Read ↗

The role of plasminogen activator inhibitor-1 polymorphism, factor-V-Leiden, and prothrombin-20210 mutations in pulmonary thromboembolism.Semantic proximity Read ↗

The 4G/5G Sequence Polymorphism in the Promoter of Plasminogen Activator Inhibitor-1 (PAI-1) Gene: Relationship to Plasma PAI-1 Level in Venous ThromboembolismSemantic proximity Read ↗

A novel G/A and the 4G/5G polymorphism within the promoter of the plasminogen activator inhibitor-1 gene in patients with deep vein thrombosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.