Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Constitutive expression of PcsB suppresses the requirement for the essential VicR (YycF) response regulator in <i>Streptococcus pneumoniae</i> R6<sup>§</sup>

17 Nov 2003

Abstract excerpt

We report several new findings about the function of the essential VicRK two-component regulatory system (TCS) in the human pathogen Streptococcus pneumoniae. The vicR-encoded response regulator, vicK-encoded histidine kinase and the protein encoded by the downstream vicX gene are the homologues of the YycF, YycG and YycJ proteins, respectively, studied previously in Bacillus subtilis and Staphylococcus aureus....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Antimicrobial Resistance in Staphylococcus
Share to Pneumonia and Respiratory Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14651645
DOI: 10.1046/j.1365-2958.2003.03806.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Constitutive expression of PcsB suppresses the requirement for the essential VicR (YycF) response regulator in <i>Streptococcus pneumoniae</i> R6<sup>§</sup>PMID 14651645Read ↗

A genomic analysis of two‐component signal transduction in <i>Streptococcus pneumoniae</i>Semantic proximity Read ↗

Localization and Cellular Amounts of the WalRKJ (VicRKX) Two-Component Regulatory System Proteins in Serotype 2Streptococcus pneumoniaeSemantic proximity Read ↗

Expression of the Streptococcus mutans essential two-component regulatory system VicRK is pH and growth-phase dependent and controlled by the LiaFSR three-component regulatory systemSemantic proximity Read ↗

Defective cell wall synthesis in Streptococcus pneumoniae R6 depleted for the essential PcsB putative murein hydrolase or the VicR (YycF) response regulator.Semantic proximity Read ↗

Eukaryotic-type serine/threonine protein kinase StkP is a global regulator of gene expression in Streptococcus pneumoniae.Semantic proximity Read ↗

A biochemical characterization of the DNA binding activity of the response regulator VicR from Streptococcus mutans.Semantic proximity Read ↗

Serine/Threonine Protein Kinase Stk Is Required for Virulence, Stress Response, and Penicillin Tolerance in Streptococcus pyogenesSemantic proximity Read ↗

A VicRK signal transduction system in Streptococcus mutans affects gtfBCD, gbpB, and ftf expression, biofilm formation, and genetic competence development.Semantic proximity Read ↗

CovS/CovR of group B streptococcus: a two‐component global regulatory system involved in virulenceSemantic proximity Read ↗

Characterization of mutants deficient in the L,D-carboxypeptidase (DacB) and WalRK (VicRK) regulon, involved in peptidoglycan maturation of Streptococcus pneumoniae serotype 2 strain D39.Semantic proximity Read ↗

Repression of virulence genes by phosphorylation‐dependent oligomerization ofCsrR at target promoters in <i>S. pyogenes</i>Semantic proximity Read ↗

An amino‐terminal signal peptide of Vfr protein negatively influences RopB‐dependent SpeB expression and attenuates virulence in <i>Streptococcus pyogenes</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.