Article
Isolation of purine auxotrophic mutants of Lactococcus lactis and characterization of the gene hpt encoding hypoxanthine guanine phosphoribosyltransferase.
Molecular & general genetics : MGG - 1 Nov 1992
Nilsson D, Lauridsen A A
Abstract excerpt
Five purine auxotrophic mutants of Lactococcus lactis were isolated. L. lactis was capable of converting adenine, guanine and hypoxanthine to AMP, GMP and IMP, respectively, indicating the existence of adenine phosphoribosyltransferase (APRT) and hypoxanthine guanine phosphoribosyltransferase (HG...
Topics
- Adenine Phosphoribosyltransferase
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA, Bacterial
- Escherichia coli
- Genes, Bacterial
- Genetic Complementation Test
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Lactococcus lactis
- Molecular Sequence Data
- Mutation
- Plasmids
- Protein Biosynthesis
- Purines
- Recombinant Proteins