The gene for hypoxanthine phosphoribosyl transferase of Plasmodium falciparum complements a bacterial HPT mutation.

doi:10.1016/0166-6851(90)90191-n

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Article

The gene for hypoxanthine phosphoribosyl transferase of Plasmodium falciparum complements a bacterial HPT mutation.

Molecular and biochemical parasitology - 1 Jun 1990

Shahabuddin M, Scaife J

Abstract excerpt

The enzyme hypoxanthine phosphoribosyl transferase of Plasmodium falciparum has been overexpressed in Escherichia coli. The protein was found to be active enzymatically. When the recombinant expression vector (pPfPRT2) was transformed and expressed in a Salmonella typhimurium mutant KP1684 (purE...

Topics

Animals
Cloning, Molecular
Escherichia coli
Gene Expression Regulation, Bacterial
Genetic Complementation Test
Hypoxanthine Phosphoribosyltransferase
Mutation
Plasmodium falciparum
Salmonella typhimurium
Substrate Specificity

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