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Article

Cloning and verification of the Lactococcus lactis pyrG gene and characterization of the gene product, CTP synthase.

The Journal of biological chemistry - 12 Oct 2001

Wadskov-Hansen S L, Willemoës M, Martinussen J, Hammer K, Neuhard J, Larsen S

Abstract excerpt

The pyrG gene of Lactococcus lactis subsp. cremoris, encoding CTP synthase, has been cloned and sequenced. It is flanked upstream by an open reading frame showing homology to several aminotransferases and downstream by an open reading frame of unknown function. L. lactis strains harboring disrupted pyrG alleles were constructed. These mutants required cytidine for growth, proving that in L. lactis, the pyrG...

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Identifiers

PMID: 11500486
DOI: 10.1074/jbc.M100531200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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