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Article

Immunoreactive androgen receptor expression in subjects with androgen resistance.

The Journal of clinical endocrinology and metabolism - 1 Dec 1992

Wilson C M, Griffin J E, Wilson J D, Marcelli M, Zoppi S, McPhaul M J

Abstract excerpt

Individuals with androgen resistance encompass a spectrum of phenotypic abnormalities ranging from complete testicular feminization to undervirilized men. Such subjects have been classified according to the hormone-binding characteristics in genital skin fibroblasts and on the basis of the mutation in the androgen receptor (AR) gene. Antibodies to the amino-terminal region of the human AR were used to develop an...

Topics

Androgens
Binding Sites
Cell Count
Drug Resistance
Electrophoresis, Polyacrylamide Gel
Fibroblasts
Humans
Immunoblotting
Ligands
Male
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Androgen

Reference Values

Skin

Source

Identifiers

PMID: 1464650
DOI: 10.1210/jcem.75.6.1464650

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1464650-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Immunoreactive androgen receptor expression in subjects with androgen resistance.PMID 1464650Read ↗

Immunoreactive AR and genetic alterations in subjects with androgen resistance and undetectable AR levels in genital skin fibroblast ligand-binding assays.Semantic proximity Read ↗

Molecular defects of the androgen receptor.Semantic proximity Read ↗

Amino acid substitutions in the DNA-binding domain of the human androgen receptor are a frequent cause of receptor-binding positive androgen resistance.Semantic proximity Read ↗

Androgen receptor mutations and androgen insensitivity.Semantic proximity Read ↗

Complete testicular feminization caused by an amino-terminal truncation of the androgen receptor with downstream initiation.Semantic proximity Read ↗

Amino acid substitutions in the hormone-binding domain of the human androgen receptor alter the stability of the hormone receptor complex.Semantic proximity Read ↗

A mutation in the DNA-binding domain of the androgen receptor gene causes complete testicular feminization in a patient with receptor-positive androgen resistance.Semantic proximity Read ↗

Androgen receptor binding studies on heterozygotes in a family with androgen insensitivity syndrome.Semantic proximity Read ↗

Androgen receptor isoforms AR-A and AR-B display functional differences in cultured human bone cells and genital skin fibroblasts.Semantic proximity Read ↗

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