Article
Androgen receptor binding studies on heterozygotes in a family with androgen insensitivity syndrome.
Biochemical and molecular medicine - 1 Jun 1995
MacLean H E, Chu S, Joske F, Warne G L, Zajac J D
Abstract excerpt
A large family with androgen insensitivity syndrome (AIS) has been investigated, in order to detect carrier individuals and to investigate their AR binding. We have previously reported that different affected members of this family have different AR gene deletions, and, testing normal female relatives of the affected individuals, we have identified three heterozygote females all of whom carry a deletion of exon E...
Topics
- Adult
- Androgens
- Bone Density
- Cells, Cultured
- Child
- Disorders of Sex Development
- Female
- Fibroblasts
- Genitalia
- Heterozygote
- Humans
- Male