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Article

Androgen receptor isoforms AR-A and AR-B display functional differences in cultured human bone cells and genital skin fibroblasts.

Steroids - 1 Dec 2003

Liegibel Ute M, Sommer Ulrike, Boercsoek Irma, Hilscher Ulrike, Bierhaus Angelika, Schweikert Hans Udo, Nawroth Peter, Kasperk Christian

Abstract excerpt

Two isoforms of the androgen receptor (AR-A and AR-B), differing by a lack of the first 187 amino acids in the NH2-terminal transactivation domain of AR-A, are expressed in connective tissue and bone. Transient transfections of normal human osteoblastic cells (HOB) and of genital skin fibroblasts defective in AR (GSF-540) were utilized to compare the functional properties of AR isoforms in mesenchymal tissues....

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Identifiers

PMID: 14643880
DOI: 10.1016/j.steroids.2003.08.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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